Tesamorelin

Description

Overview

Tesamorelin is a stabilized synthetic analogue of growth-hormone-releasing hormone (GHRH). It is engineered to stimulate the pituitary to release endogenous growth hormone (GH) while preserving physiological pulsatility, thereby offering a model to examine GH/IGF-1 axis dynamics, visceral fat modulation and metabolic signalling.

This peptide is particularly used in pre-clinical research for investigating how endogenous GH release can impact body composition, lipid metabolism, visceral adipose tissue (VAT) and associated biochemical pathways. For example, studies show tesamorelin significantly reduces visceral fat and liver fat in specific populations.

Product Details

• Type: Synthetic GHRH analogue
• Typical Molecular Formula / Weight: approx. C₂₂₃H₃₇₀N₇₂O₆₉S ; MW ~5,195.9 g/mol
• CAS Number / PubChem CID: CAS 901758-09-6 ; PubChem CID 44147413
• Research Status: Provided as research-grade material only; not approved for therapeutic, diagnostic or veterinary use
• Intended Use: Laboratory and pre-clinical experimental models only

Research Applications

• Growth Hormone Axis Modulation: Useful for studying how GHRH-type peptides activate GH release, and the downstream IGF-1 signalling cascade.
• Visceral Fat & Metabolic Signalling Research: Employed in models showing reductions in VAT and liver fat, making it a tool for exploring adiposity, lipolysis and metabolic health parameters.
• Body Composition & Endocrine Studies: Used in non-clinical settings investigating GH-mediated lean mass support, visceral fat reduction, and metabolic biomarker changes.
• Peptide Design & Stability Research: Because it’s a modified form of GHRH with improved stability, it is applicable in studies evaluating peptide engineering, half-life extension and receptor kinetics.

Usage & Safety

This product is strictly for laboratory research use only. It is not approved for human or veterinary consumption and should not be used for diagnostic, therapeutic or cosmetic applications. Always follow institutional biosafety guidelines, proper reconstitution and storage protocols appropriate for peptides.

Disclaimer

All information provided is for educational and scientific research purposes only. This material is not intended to diagnose, treat, cure, or prevent any disease. Not for human or veterinary use.