Cagrilintide

Description

Overview

Cagrilintide is a lipidated, long-acting synthetic peptide analogue of the endogenous hormone amylin (islet amyloid polypeptide), engineered to provide enhanced stability and extended receptor activation. It acts as a dual amylin and calcitonin receptor agonist (DACRA), making it a valuable tool in research into appetite regulation, energy homeostasis, glucose metabolism and adiposity.
This peptide is increasingly used in preclinical models to explore analogues of next-generation metabolic therapeutics.

Product Details

• Analogue Type: Long-acting amylin analogue / calcitonin receptor agonist (DACRA)
• Molecular Weight & Formula: For reference – approx 4,409 g/mol, formula C₁₉₄H₃₁₂N₅₄O₅₉S₂ (per supplier annotation)
• CAS Number: 1415456-99-3
• Research Status: Research-grade only; not approved for human therapeutic use.

Research Applications

• Appetite & Energy Homeostasis: Used in studies analysing how amylin receptor signalling influences satiety, caloric intake and neural control of feeding behaviour.
• Glucose & Metabolic Regulation: Employed in models of obesity, type 2 diabetes and metabolic syndrome to study combined receptor modulation effects.
• Peptide Design & Comparative Pharmacology: Offers researchers a platform to examine how receptor dual-agonism and protein engineering (lipidation, half-life extension) influence pharmacodynamics in preclinical settings.
• Combination Research: Often investigated in conjunction with other peptides/agonists (e.g., GLP-1 analogues) to probe synergistic metabolic effects.

Usage & Safety

This product is intended for laboratory research use only, and is not approved for human or veterinary applications. Not for diagnostic or therapeutic use. Users must adhere to institutional safety protocols, handle via appropriate laboratory procedures, and store according to supplier guidelines to maintain integrity.

Disclaimer

All content is provided for educational and scientific research purposes only. This material is not intended to diagnose, treat, cure or prevent any disease. Not for human consumption.