5-amino-1mq

Description

Overview

5-Amino-1MQ is a synthetic small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). NNMT is implicated in adipose tissue metabolism, NAD⁺ salvage pathways, and has been associated with metabolic disorders such as obesity and type-2 diabetes. By inhibiting NNMT, 5-Amino-1MQ helps shift cellular metabolism away from fat storage and toward increased NAD⁺ availability and energy utilization.

Product Details

• Compound Type: Small-molecule NNMT inhibitor
• Typical Molecular Formula / Weight: (Not always publicly disclosed in all listings)
• Status: Research-grade material only; not approved for therapeutic, diagnostic or veterinary
• Primary Focus: Laboratory and preclinical models investigating metabolic signalling, adipose    tissue/obesity mechanisms and NAD⁺-related pathways
• CAS Number: 42464-96-0

Research Applications

• Adipose Tissue & Metabolic Modelling: Used in studies showing reduction in adipocyte size, lipid accumulation and white adipose tissue mass in diet-induced obese (DIO) animal models.
•  NAD⁺ & Cellular Energy Metabolism: Helps researchers probe how boosted NAD⁺ levels influence mitochondrial function, cellular energy expenditure, and metabolic regulation.
• Anti-Aging / Longevity Signalling Models: Applied in mechanistic research related to sirtuin activation, cellular stress response, and metabolic health in ageing models.
• Mechanistic Enzyme Inhibition Research: Supports investigations into NNMT enzyme kinetics, cellular methylation status, and downstream metabolic consequences.
•  Usage & Safety
  This compound is strictly for laboratory research use only. It is not approved for human or veterinary use, and should not be used for therapeutic or diagnostic purposes. Proper laboratory safety procedures, aseptic handling, and appropriate storage conditions must be followed.

Disclaimer

All information provided is for educational and scientific research purposes only. This material is not intended to diagnose, treat, cure, or prevent any disease. Not for human or veterinary consumption.