Description
Overview
HGH Fragment 176-191 is a synthetic piece of the human growth hormone (hGH) molecule, specifically the C-terminal region (amino acids 176 to 191). This fragment has been studied in preclinical research for its targeted fat-metabolism effects while avoiding many of the broad systemic actions of full-length hGH.
Researchers use this fragment to explore fat-breakdown (lipolysis), reduced fat storage (antilipogenesis), cartilage repair, and metabolic signaling without inducing the growth-stimulating effects typical of full hGH.
Product Details
- Sequence: Phe-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
- Typical Molecular Formula / Weight: C₇₈H₁₂₃N₂₃O₂₂S₂; MW ~1,799.1 g/mol
- Status: Research-grade material; not approved for therapeutic, diagnostic or veterinary use
- Purity: Laboratory specification (check batch COA)
- Intended Use: Pre-clinical research, metabolic modelling, peptide signaling studies
- CAS Number: 221231-10-3
Research Applications
- Fat-Metabolism & Lipolysis Studies: Applied in models examining the effect of this fragment on fat cell breakdown, adipocyte signaling, and energy expenditure.
- Metabolic Regulation: Utilized in research of how the fragment modulates insulin sensitivity, glucose balance, and adipose tissue biology.
- Cartilage & Tissue Repair Research: Explored for its potential in cartilage regeneration and connective tissue repair in preclinical models.
- Peptide-Receptor Design & Mechanism Studies: Serves as a model for how truncated growth-hormone fragments can target specific pathways with reduced off-target anabolic effects.
Usage & Safety
This product is intended for laboratory research use only. It is not approved for human or veterinary use, and must not be used for diagnostic, therapeutic or cosmetic applications. Researchers must handle with appropriate lab safety procedures and store under recommended peptide storage conditions (e.g., protected from moisture/light, typically frozen dry until use).
Disclaimer
All information provided is for educational and scientific research purposes only. This material is not intended to diagnose, treat, cure, or prevent any disease. Not for human or veterinary consumption.





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