CJC-1295 With DAC

Description

Overview

HCG is a recombinant or purified glycoprotein hormone comprised of an α-subunit (shared with LH/FSH/TSH) and a distinct β-subunit, forming a heterodimer with a molecular mass of approximately 36.7 kDa.

In research settings, HCG is employed as a tool to model gonadotropin receptor (LHCGR) activation, downstream steroidogenic enzyme induction, and endocrine-axis feedback dynamics.

Product Details

• Type: Glycoprotein hormone (LH/CG family)
• Typical Molecular Weight: ~36.7 kDa
• Mechanism: Binds the luteinizing/chorionic gonadotropin receptor (LHCGR) to activate cAMP-mediated pathways and stimulate steroidogenesis in target cells.
• Research Status: Provided for laboratory research use only; not approved for therapeutic, diagnostic or veterinary use.
• Typical Format: Lyophilized vial, highly purified, suitable for in-vitro and preclinical models.
• CAS Number: 863288-34-0

Research Applications

• Gonadotropin Receptor Signaling: Used in studies of LHCGR activation, intracellular cAMP production, gene expression changes and steroidogenic enzyme up-regulation.
• Endocrine Axis Modelling: Employed to examine feedback loops between the hypothalamus, pituitary and gonadal axes in cell and animal models.
• Steroidogenesis Assays: Utilized in investigations of Leydig and granulosa cell function, progesterone/testosterone biosynthesis, and receptor-agonist kinetics.
• Glycoprotein Hormone Structure & Mechanism Research: Serves as a model for exploring glycosylation, half-life extension (via C-terminal peptide in β-subunit), and receptor binding kinetics.

Usage & Safety

This material is intended for laboratory research use only. It is not approved for human or veterinary use, and should not be used for therapeutic, diagnostic, cosmetic or supplement purposes. Handle in compliance with institutional laboratory safety protocols and store under recommended peptide/hormone storage conditions (typically ≤ -20 °C for lyophilized material).

Disclaimer

All information provided herein is for educational and scientific research purposes only. This material is not intended to diagnose, treat, cure or prevent any disease. Not for human or veterinary consumption.